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    Anesthetic approach to the patients with scleroderma at coronary artery surgery: two case reports
    (EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL, 2011) Aksoy, Tamer; Haberal, Ismail; Erturk, Esra; Zorman, Yilmaz; Akyildiz, Mahmut; Findik, Orhan
    Scleroderma is a progressive connective tissue disease characterized by multiple-organ involvement. Altough the lesions are mostly seen in microvascular bed, in rare cases coronary and peripheral arteries are also affected. In this article, we report the problems and management strategies in two scleroderma patients at an intensive care unit after coronary artery bypass surgery.
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    Carotid enaarterectomy with cervical blockage
    (EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL, 2011) Akyildiz, Mahmut; Erden, Benay; Onar, L. Cagatay
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    Carotid endarterectomy with cervical blockage Author's response
    (EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL, 2011) Akyildiz, Mahmut; Erden, Benay; Onar, L. Cagatay
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    A comparision of the sensitivity and specificity of the EuroSCORE, Cleveland, and CABDEAL risk stratification systems in the Turkish population
    (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2012) Findik, Orhan; Haberal, Ismail; Akyildiz, Mahmut; Aksoy, Tamer; Erturk, Esra; Zorman, Yilmaz; Zengin, Mustafa
    Background: In this study, we aimed to compare three risk stratification systems to establish which of them is more suitable for predicting mortality and morbidity rates in the Turkish population. Methods: Our retrospective study included 501 consecutive patients (366 males, 135 females; mean age 63.4 +/- 19.4 years; range 44 to 83. years) who underwent coronary artery bypass graft (CABG) surgery between February 2005 and December 2006 in our clinic. The preoperative and intraoperative risk factors of the Cleveland, EuroSCORE, and CABDEAL risk stratification systems were analyzed for each patient, and the sensitivity and specificity of these three systems were compared in terms of mortality and morbidity. Results: In terms of mortality, the sensitivity and the specificity of the Cleveland system was found to be 61.5% and 90.4%, respectively while for the EuroSCORE system, the rates were 92.3% and 82.2%, respectively. For the CABDEAL system, the sensitivity and specificity were 92.3% and 44.9%, respectively. In terms of morbidity, the sensitivity and specificity of Cleveland system were 23.5% and 89.5%, respectively, while they were 41.2% and 81%, respectively for the EuroSCORE. The sensitivity and specificity of the CABDEAL system were 82.4% and 44.8%, respectively. Conclusion: The. study results showed that the EuroSCORE system is more suitable for predicting the expected mortality rates while the CABDEAL system followed by the Cleveland system are more appropriate in for predicting the expected morbidity rates in the Turkish population with cardiac disease.
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    Giant Floating Thrombus Localized in the Ascending Aorta
    (FORUM MULTIMEDIA PUBLISHING, LLC, 2010) Akyildiz, Mahmut; Zorman, Yilmaz; Aksoy, Tamer; Yilmazer, Mustafa S.; Erturk, Esra; Onar, Cagatay L.; Midi, Ahmet
    We report the case of a 32-year-old male patient with symptoms of cerebrovascular accident manifesting with dysarthria. A transesophageal echocardiogram showed a floating mass localized in the ascending aorta, and a multislice computed tomography evaluation confirmed the diagnosis. With a comprehensive assessment of the mass, we decided on surgical intervention. A pedunculated and fragile mass was seen just near the right coronary ostium. The measured dimensions were 7.7 x 1.0 x 1.5 cm. The removed mass has been analyzed histopathologically and found to be the cause of the neurologic findings with an uncertain underlying etiology.
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    Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting
    (KARGER, 2007) Aksungar, Fehime B.; Topkaya, Aynur E.; Akyildiz, Mahmut
    Background: It is well known that nutritional habits, sleeping patterns and meal frequency have profound effects on maintaining human health. Ramadan is a religious month for Islam, during which Muslims do not eat and drink during the daylight hours. The duration of restricted food and beverage intake is approximately 12 h/day for 1 month, which makes Ramadan a model of prolonged intermittent fasting. Methods: In order to evaluate the effects of long- lasting modifications of food intake on inflammatory markers and biochemical parameters 40 healthy volunteers of normal weight [ 20 females aged between 20 and 38 years, 20 males aged between 23 and 39 years, body mass index (BMI) < 25 kg/m(2)] who fasted during Ramadan and another 28 healthy age and BMI-matched volunteers (14 males, 14 females) who did not fast participated in the study. Venous blood samples were taken 1 week before Ramadan, during the last week of Ramadan and 3 weeks after Ramadan. Serum interleukin-6 (IL-6), C-reactive protein (CRP), homocysteine, vitamin B-12, folate, total cholesterol (TC), triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels were measured. Results: No significant changes were observed in serum total cholesterol, triglycerides and LDL levels. TC/HDL ratio (HDL risk factor) was decreased during and after Ramadan in both genders in the fasting group while there were no changes in the nonfasting group. IL-6 (p < 0.001), CRP (p < 0.001) and homocysteine (p < 0.01) levels were significantly low during Ramadan in the fasting subjects of both genders when compared to basal values (1 week before Ramadan). Conclusion: Our results demonstrate that prolonged intermittent fasting in a model like Ramadan has some positive effects on the inflammatory status of the body and on the risk factors for cardiovascular diseases such as homocysteine, CRP and TC/HDL ratio. Copyright (c) 2007 S. Karger AG, Basel
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    On-pump coronary bypass surgery in a pseudothrombocytopenic patient: a case report
    (EKIN TIBBI YAYINCILIK LTD STI-EKIN MEDICAL PUBL, 2011) Haberal, Ismail; Akyildiz, Mahmut; Aksoy, Tamer; Zorman, Yilmaz; Erturk, Esra; Zengin, Mustafa
    A sixty-year-old female patient was admitted to our cardiovascular surgery department for coronary bypass surgery. Coronar angiograpy revealed three vessel coronary artery disease. The patient's preoperative whole blood count examination was performed by taking whole blood into EDTA tubes. The platelet count was found to be 23x10(3)/mm(3). The patient has no bleeding problem. In the physical examination; no pathologies were detected other than bilateral basal fine crepitations in the lungs and the result of bleeding and coagulation tests were normal. In the peripheral blood smear examination, adequate platelet clusters were found. Since the laboratory findings were normal and the patient had no history of bleeding problems, the patient was diagnosed with EDTA-dependent pseudothrombocytopenia. We presented this case to emphasize the importance of preoperative platelet count and function and remind of the issue of pseudothrombocytopenia.